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What are some ways ENHERTU4U may be able to help after I've been prescribed ENHERTU?

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ACCESS

ENHERTU4U is here to help your healthcare provider understand your insurance company's requirements for access to treatment with ENHERTU.

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Financial
Assistance

We have multiple options to help you afford your treatment. Your healthcare provider can provide more information about how ENHERTU4U may be able to help.

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Nursing
Support

ENHERTU4U has nurses available to speak to you and answer questions about your treatment.

Nurses are available 8 AM - 8 PM ET, Monday to Friday.

ENHERTU (fam-trastuzumab deruxtecan-nxki) 20 mg/mL Injection 4U logo ENHERTU (fam-trastuzumab deruxtecan-nxki) 20 mg/mL Injection 4U logo

For support from ENHERTU4U, please call 1-833-ENHERTU
(1-833-364-3788)
or visit www.ENHERTU4U.com.

ENHERTU4U does not guarantee access or cost savings for patients prescribed ENHERTU.

Are there resources I can download?

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Become more familiar with ENHERTU, including the potential benefits and risks of treatment

Download Patient Brochure
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Find helpful information and suggestions to help you understand and manage potential side effects

Download Side Effects Brochure
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Learn how ENHERTU4U may be able to help you determine your insurance coverage, access your treatment and explore financial assistance options after you've been prescribed ENHERTU

Download Access and Affordability Brochure
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Communicate with healthcare providers not involved with your ENHERTU treatment

Download
Wallet Card
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Learn tips and strategies for helping a loved one during treatment with ENHERTU

Download Caregiver Brochure
Would you like us to send you information about ENHERTU when it becomes available?

What is the most important information I should know about ENHERTU?
ENHERTU can cause serious side effects, including:
Lung problems that may be severe, life-threatening or that may lead to death.
If you develop lung problems your healthcare provider may treat you with corticosteroid medicines. Tell your healthcare provider right away if you get any of the following signs and symptoms:

  • Cough
  • Trouble breathing or shortness of breath
  • Fever
  • Other new or worsening breathing symptoms (e.g., chest tightness, wheezing)

Low white blood cell count (neutropenia). Low white blood cell counts are common with ENHERTU and can sometimes be severe. Your healthcare provider will check your white blood cell counts before starting ENHERTU and before starting each dose. Tell your healthcare provider right away if you develop any signs or symptoms of an infection or have fever or chills during treatment with ENHERTU.

Heart problems that may affect your heart’s ability to pump blood. Your healthcare provider will check your heart function before starting treatment with ENHERTU. Tell your healthcare provider right away if you get any of the following signs and symptoms:

  • New or worsening shortness of breath
  • Coughing
  • Feeling tired
  • Swelling of your ankles or legs
  • Irregular heartbeat
  • Sudden weight gain
  • Dizziness or feeling light-headed
  • Loss of consciousness

Your healthcare provider will check you for these side effects during your treatment with ENHERTU. Your healthcare provider may reduce your dose, delay treatment or completely stop treatment with ENHERTU if you have severe side effects.

Harm to your unborn baby. Tell your healthcare provider right away if you become pregnant or think you might be pregnant during treatment with ENHERTU.

  • If you are able to become pregnant, your healthcare provider should do a pregnancy test before you start treatment with ENHERTU.
  • Females who are able to become pregnant should use effective birth control (contraception) during treatment with ENHERTU and for at least 7 months after the last dose.
  • Males who have female partners that are able to become pregnant should use effective birth control (contraception) during treatment with ENHERTU and for at least 4 months after the last dose.

Before you receive ENHERTU, tell your healthcare provider about all of your medical conditions, including if you:

  • Have lung or breathing problems.
  • Have signs or symptoms of an infection.
  • Have or have had any heart problems.
  • Are breastfeeding or plan to breastfeed. It is not known if ENHERTU passes into your breast milk. Do not breastfeed during treatment with ENHERTU and for 7 months after the last dose.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How will I receive ENHERTU?

  • You will receive ENHERTU into your vein through an intravenous (IV) line by your healthcare provider.
  • ENHERTU is given 1 time every three weeks (21-day treatment cycle).
  • Your healthcare provider will decide how many treatments you need.
  • Your healthcare provider may slow down or temporarily stop your infusion of ENHERTU if you have an infusion-related reaction, or permanently stop ENHERTU if you have severe infusion reactions.
  • If you miss a planned dose of ENHERTU, call your healthcare provider right away to schedule an appointment. Do not wait until the next planned treatment cycle.

What are the possible side effects of ENHERTU?
ENHERTU can cause serious side effects. See "What is the most important information I should know about ENHERTU?"

The most common side effects of ENHERTU include:

  • Nausea
  • Feeling tired
  • Vomiting
  • Hair loss
  • Constipation
  • Decreased appetite
  • Low red blood cell counts
  • Low white blood cell counts
  • Diarrhea
  • Cough
  • Low platelet counts

ENHERTU may cause fertility problems in males, which may affect the ability to father children. Talk to your healthcare provider if you have concerns about fertility.

These are not all of the possible side effects of ENHERTU. Call your doctor for medical advice about side effects. You may report side effects to Daiichi Sankyo at 1-877-437-7763 or to FDA at 1-800-FDA-1088.

What is ENHERTU?

ENHERTU is a prescription medicine used in adults to treat human epidermal growth factor receptor 2 (HER2)-positive breast cancer that cannot be removed by surgery or that has spread to other parts of your body (metastatic), and who have received two or more prior anti-HER2 breast cancer treatments.

ENHERTU was FDA approved for this use based on a clinical study that measured how many patients responded and how long they responded. ENHERTU is still being studied to confirm these results.

It is not known if ENHERTU is safe and effective in children.

Please click here for full Prescribing Information, including Boxed WARNING, and click here for Medication Guide.

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