Links to Homepage of ENHERTU (fam-trastuzumab deruxtecan-nxki) Patient Website Links to Homepage of ENHERTU (fam-trastuzumab deruxtecan-nxki) Patient Website

ENHERTU is FDA-approved for the treatment of several types of cancer

ENHERTU is FDA-approved for the treatment of several types of cancer

Don’t know your HER2 status? Talk to your healthcare provider.
Not actual patients.
HER2, human epidermal growth factor receptor 2; HR+, hormone receptor-positive; HR–, hormone receptor-negative; mBC, metastatic breast cancer.

What is ENHERTU?

ENHERTU (en-HER-too) is a prescription medicine used to treat adults who have:

  • Human epidermal growth factor receptor 2 (HER2)-positive breast cancer that cannot be removed by surgery or that has spread to other parts of the body (metastatic), and who have received a prior anti-HER2 breast cancer treatment:
    • For metastatic disease, or
    • Have breast cancer that has come back during or within 6 months of completing treatment for their early-stage breast cancer.
  • HER2-low breast cancer that cannot be removed by surgery or that has spread to other parts of your body (metastatic), and who have received a prior chemotherapy:
    • For metastatic disease, or
    • Your disease has returned during or within 6 months of completing adjuvant chemotherapy (after surgery). Your healthcare provider will perform a test to make sure ENHERTU is right for you.
  • Non-small cell lung cancer (NSCLC) that has a certain mutation in the HER2 gene and cannot be removed by surgery or has spread to other parts of your body (metastatic), and who have received a prior treatment. Your healthcare provider will perform a test to make sure ENHERTU is right for you.

    ENHERTU was FDA approved for this use based on a clinical study that measured how many patients responded and how long they responded. ENHERTU is still being studied to confirm these results.
  • Stomach cancer called gastric or gastroesophageal junction (GEJ) adenocarcinoma that is HER2-positive and has spread to areas near your stomach (locally advanced) or that has spread to other parts of your body (metastatic), and who have received a prior trastuzumab-based regimen.
  • It is not known if ENHERTU is safe and effective in children.

Please see full Prescribing Information, including Boxed WARNINGS, and Medication Guide.